Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity.

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作者： Yu,Fu ^[1] ; Ping,Zhang ^[2] ; Jie,Ge ^[3] ; Jie,Cheng ^[2] ; Weijie,Dong ^[1] ; Hua,Yuan ^[2] ; Yifei,Du ^[2] ; Mifang,Yang ^[3] ; Ruoxing,Sun ^[3] ; Hongbing,Jiang ^[4]

作者单位： Department of Oral and Maxillofacial Surgery, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China; Institute of Stomatology, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. ^[1] Department of Oral and Maxillofacial Surgery, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. ^[2] Institute of Stomatology, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. ^[3] Department of Oral and Maxillofacial Surgery, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China; Institute of Stomatology, School of Stomatology, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China. Electronic address: jhb@njmu.edu.cn. ^[4]

关键词 Bone marrow stromal cells HDAC inhibitor Histone H3 lysine 9 acetylation Histone deacetylase 8 Osteogenic differentiation