The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.
作者:
主题词
动物(Animals);自身免疫(Autoimmunity);细胞分化(Cell Differentiation);叉头转录因子类(Forkhead Transcription Factors);白细胞介素2(Interleukin-2);Janus激酶1(Janus Kinase 1);Janus激酶3(Janus Kinase 3);小鼠(Mice);蛋白质酪氨酸磷酸酶, 非受体2型(Protein Tyrosine Phosphatase, Non-Receptor Type 2);STAT5转录因子(STAT5 Transcription Factor);信号传导(Signal Transduction);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);TNF受体相关因子3(TNF Receptor-Associated Factor 3);胸腺(Thymus Gland)
DOI
10.1038/ni.2944
PMID
25029551
发布时间
2024-06-10
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Nature immunology
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