Towards neuroimmunotherapy for cancer: the neurotransmitters glutamate, dopamine and GnRH-II augment substantially the ability of T cells of few head and neck cancer patients to perform spontaneous migration, chemotactic migration and migration towards the autologous tumor, and also elevate markedly the expression of CD3zeta and CD3epsilon TCR-associated chains.
作者:
主题词
老年人(Aged);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞运动(Cell Movement);趋化性, 白细胞(Chemotaxis, Leukocyte);多巴胺(Dopamine);谷氨酸(Glutamic Acid);促性腺素释放激素(Gonadotropin-Releasing Hormone);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);免疫疗法(Immunotherapy);男(雄)性(Male);中年人(Middle Aged);神经递质药(Neurotransmitter Agents);T淋巴细胞(T-Lymphocytes);组织培养技术(Tissue Culture Techniques)
DOI
10.1007/s00702-014-1242-y
PMID
25030361
发布时间
2023-05-25
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