Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases.

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作者： Yuquan,Xu ^[1] ; Tong,Zhou ^[2] ; Shuwei,Zhang ^[2] ; Patricia,Espinosa-Artiles ^[3] ; Luoyi,Wang ^[2] ; Wei,Zhang ^[4] ; Min,Lin ^[4] ; A A Leslie,Gunatilaka ^[5] ; Jixun,Zhan ^[6] ; István,Molnár ^[7]

作者单位： Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China; Natural Products Center, School of Natural Resources and the Environment, University of Arizona, Tucson, AZ 85706; ^[1] Department of Biological Engineering, Utah State University, Logan, UT 84322; and. ^[2] Natural Products Center, School of Natural Resources and the Environment, University of Arizona, Tucson, AZ 85706; ^[3] Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, Beijing 100081, P. R. China; ^[4] Natural Products Center, School of Natural Resources and the Environment, University of Arizona, Tucson, AZ 85706; Bio5 Institute, University of Arizona, Tucson, AZ 85721. ^[5] Department of Biological Engineering, Utah State University, Logan, UT 84322; and jixun.zhan@usu.edu imolnar@email.arizona.edu. ^[6] Natural Products Center, School of Natural Resources and the Environment, University of Arizona, Tucson, AZ 85706; Bio5 Institute, University of Arizona, Tucson, AZ 85721 jixun.zhan@usu.edu imolnar@email.arizona.edu. ^[7]

关键词 fungal genetics secondary metabolites