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Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.

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第一作者： M V,Machado

第一单位： Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA Gastroenterology Department, Hospital de Santa Maria, CHLN, Lisbon, Portugal.

作者： M V,Machado ^[1] ; G A,Michelotti ^[2] ; T de Almeida,Pereira ^[2] ; J,Boursier ^[3] ; L,Kruger ^[2] ; M,Swiderska-Syn ^[2] ; G,Karaca ^[2] ; G,Xie ^[2] ; C D,Guy ^[4] ; B,Bohinc ^[2] ; K R,Lindblom ^[5] ; E,Johnson ^[5] ; S,Kornbluth ^[5] ; A M,Diehl ^[2]

作者单位： Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA Gastroenterology Department, Hospital de Santa Maria, CHLN, Lisbon, Portugal. ^[1] Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA. ^[2] Division of Gastroenterology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA HIFIH Laboratory, UPRES 3859, SFR 4208, LUNAM University, Angers, France. ^[3] HIFIH Laboratory, UPRES 3859, SFR 4208, LUNAM University, Angers, France. ^[4] Division of Pathology, Duke University Medical Center, Durham, North Carolina, USA Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA. ^[5]

关键词 APOPTOSIS CELL DEATH FATTY LIVER MOLECULAR BIOLOGY NONALCOHOLIC STEATOHEPATITIS