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Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.

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第一作者： L,Johannesen

第一单位： 1] Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA [2] Department of Clinical Physiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

作者： L,Johannesen ^[1] ; J,Vicente ^[2] ; J W,Mason ^[3] ; C,Sanabria ^[3] ; K,Waite-Labott ^[3] ; M,Hong ^[4] ; P,Guo ^[4] ; J,Lin ^[4] ; J S,Sørensen ^[5] ; L,Galeotti ^[6] ; J,Florian ^[5] ; M,Ugander ^[1] ; N,Stockbridge ^[7] ; D G,Strauss ^[1]

作者单位： 1] Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA [2] Department of Clinical Physiology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden. ^[1] 1] Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA [2] BSICoS Group, Aragón Institute of Engineering Research (I3A), IIS Aragón, University of Zaragoza, Zaragoza, Aragon, Spain. ^[2] Spaulding Clinical Research, West Bend, Wisconsin, USA. ^[3] Frontage Laboratories, Exton, Pennsylvania, USA. ^[4] Division of Pharmacometrics, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA. ^[5] Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland, USA. ^[6] Division of Cardiovascular and Renal Products, Office of New Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA. ^[7]