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Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.

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第一作者: Yolande F M,Ramos
第一单位: Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
作者单位: Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands. [1] Department of Twin Research & Genetic Epidemiology, King's College London, London, UK. [2] NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK Arthritis Research UK, Sport, Exercise and Osteoarthritis Centre of Excellence, London, UK. [3] Department of Rheumatology, Nordic Bioscience, Herlev, Denmark. [4] Department of Gerontology and Geriatrics, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands. [5] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA The Framingham Heart Study, Framingham, Massachusetts, USA. [6] Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia Department of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA Broad Institute, Cambridge, Massachusetts, USA. [7] Department of Hygiene & Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece Department of Twin Research & Genetic Epidemiology, King's College London, London, UK. [8] Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA. [9] Department of Hygiene & Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece Department of Medicine, Stanford Prevention Research Center, Stanford, USA Department of Health Research and Policy, Stanford University School of Medicine, Stanford, USA Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, USA. [10] Department of Rheumatology & Clinical Epidemiology, LUMC, Leiden, The Netherlands. [11] Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, The Netherlands. [12] Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia. [13] Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK. [14] The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands. [15] Global Analytical Science, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA. [16] Academic Rheumatology, University of Nottingham, Nottingham, UK. [17]
DOI 10.1136/jmedgenet-2014-102478
PMID 25057126
发布时间 2020-12-09
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Journal of medical genetics

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