换一批Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
第一作者：
Akito,Nakagawa
第一单位：
Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, Massachusetts 02114, United States.
作者：
主题词
贫血, 镰状细胞性(Anemia, Sickle Cell);结晶学, X线(Crystallography, X-Ray);二硫化物类(Disulfides);红细胞(Erythrocytes);血红蛋白, 镰状(Hemoglobin, Sickle);血红蛋白类(Hemoglobins);溶血(Hemolysis);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);分子结构(Molecular Structure);氧(Oxygen);蛋白质构象(Protein Conformation);小分子化合物库(Small Molecule Libraries);三唑类(Triazoles)
DOI
10.1021/cb500230b
PMID
25061917
发布时间
2022-03-17
- 浏览5
ACS chemical biology
2318-25页
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