Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.-论文-万方医学网

作者： Xiang-Sheng,Zhang ^[1] ; Xin,Zhang ^[2] ; Qi,Wu ^[3] ; Wei,Li ^[4] ; Qing-Rong,Zhang ^[5] ; Chun-Xi,Wang ^[6] ; Xiao-Ming,Zhou ^[1] ; Hua,Li ^[7] ; Ji-Xin,Shi ^[8] ; Meng-Liang,Zhou ^[9]

作者单位： Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. xiaoming20111386@163.com. ^[1] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. zhangxsp@163.com. ^[2] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. njwuqi@gmail.com. ^[3] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. lwxzlw@gmail.com. ^[4] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. njzhangqingrong@aliyun.com. ^[5] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. wangcx02@163.com. ^[6] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. solihua@gmail.com. ^[7] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. shijx52@hotmail.com. ^[8] Department of Neurosurgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210000, Jiangsu, China. mlzhou1979@hotmail.com. ^[9]

主题词动物(Animals);细胞凋亡(Apoptosis);血脑屏障(Blood-Brain Barrier);脑损伤(Brain Injuries);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);大脑皮质(Cerebral Cortex);疾病模型, 动物(Disease Models, Animal);减量调节(Down-Regulation);男(雄)性(Male);神经元(Neurons);神经保护药(Neuroprotective Agents);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);信号传导(Signal Transduction);蛛网膜下腔出血(Subarachnoid Hemorrhage);增量调节(Up-Regulation);黄叶素(Xanthophylls);bcl相关死亡蛋白质(bcl-Associated Death Protein)

DOI 10.3390/md12084291

PMID 25072152

发布时间 2024-12-27

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Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.

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Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling.

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