换一批
换一批Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.
作者：
Clive J,Hoggart [1]
;
Giulia,Venturini [2]
;
Massimo,Mangino [3]
;
Felicia,Gomez [4]
;
Giulia,Ascari [2]
;
Jing Hua,Zhao [5]
;
Alexander,Teumer [6]
;
Thomas W,Winkler [7]
;
Natalia,Tšernikova [8]
;
Jian'an,Luan [5]
;
Evelin,Mihailov [9]
;
Georg B,Ehret [10]
;
Weihua,Zhang [11]
;
David,Lamparter [12]
;
Tõnu,Esko [13]
;
Aurelien,Macé [12]
;
Sina,Rüeger [12]
;
Pierre-Yves,Bochud [14]
;
Matteo,Barcella [15]
;
Yves,Dauvilliers [16]
;
Beben,Benyamin [17]
;
David M,Evans [18]
;
Caroline,Hayward [19]
;
Mary F,Lopez [20]
;
Lude,Franke [21]
;
Alessia,Russo [22]
;
Iris M,Heid [7]
;
Erika,Salvi [15]
;
Sailaja,Vendantam [23]
;
Dan E,Arking [24]
;
Eric,Boerwinkle [25]
;
John C,Chambers [11]
;
Giovanni,Fiorito [22]
;
Harald,Grallert [26]
;
Simonetta,Guarrera [27]
;
Georg,Homuth [6]
;
Jennifer E,Huffman [19]
;
David,Porteous [28]
;
Generation Scotland Consortium [29]
;
LifeLines Cohort study [30]
;
GIANT Consortium [31]
;
Darius,Moradpour [32]
;
Alex,Iranzo [33]
;
Johannes,Hebebrand [34]
;
John P,Kemp [35]
;
Gert J,Lammers [36]
;
Vincent,Aubert [37]
;
Markus H,Heim [38]
;
Nicholas G,Martin [30]
;
Grant W,Montgomery [39]
;
Rosa,Peraita-Adrados [40]
;
Joan,Santamaria [5]
;
Francesco,Negro [3]
;
Carsten O,Schmidt [41]
;
Robert A,Scott [40]
;
Tim D,Spector [5]
;
Konstantin,Strauch [3]
;
Henry,Völzke [3]
;
Nicholas J,Wareham [24]
;
Wei,Yuan [42]
;
Jordana T,Bell [43]
;
Aravinda,Chakravarti [22]
;
Jaspal S,Kooner [44]
;
Annette,Peters [36]
;
Giuseppe,Matullo [45]
;
Henri,Wallaschofski [46]
;
John B,Whitfield [12]
;
Fred,Paccaud [47]
;
Peter,Vollenweider [48]
;
Sven,Bergmann [19]
;
Jacques S,Beckmann [15]
;
Mehdi,Tafti [45]
;
Nicholas D,Hastie [49]
;
Daniele,Cusi [50]
;
Murielle,Bochud [51]
;
Timothy M,Frayling [52]
;
Andres,Metspalu [32]
;
Marjo-Riitta,Jarvelin [4]
;
André,Scherag [45]
;
George Davey,Smith [13]
;
Ingrid B,Borecki [2]
;
Valentin,Rousson [53]
;
Joel N,Hirschhorn [54]
;
Carlo,Rivolta ;
Ruth J F,Loos ;
Zoltán,Kutalik
作者单位：
Department of Genomics of Common Disease, Imperial College London, London, United Kingdom.
[1]
Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.
[2]
Department of Twin Research & Genetic Epidemiology, King's College London, London, United Kingdom.
[3]
Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
[4]
MRC-Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
[5]
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
[6]
Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.
[7]
Estonian Genome Center, University of Tartu, Tartu, Estonia; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
[8]
Estonian Genome Center, University of Tartu, Tartu, Estonia; Estonian Biocentre, Tartu, Estonia.
[9]
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Center for Complex Disease Genomics, Baltimore, Maryland, United States of America; Cardiology, Geneva University Hospitals, Geneva, Switzerland.
[10]
Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
[11]
Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
[12]
Center for Basic and Translational Obesity Research and Divisions of Endocrinology and Genetics, Boston Children's Hospital, Boston, Massachusetts, United States of America; Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.
[13]
Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[14]
Department of Health Sciences, University of Milan, Milan, Italy.
[15]
INSERM-U1061, Montpellier, France; National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia), Department of Neurology, Gui-de-Chauliac Hospital, Montpellier, France.
[16]
Queensland Brain Institute, University of Queensland, Brisbane, Australia; Genetic Epidemiology, QIMR Berghofer Institute of Medical Research, Brisbane, Australia.
[17]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, Australia.
[18]
MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
[19]
Center for Basic and Translational Obesity Research and Divisions of Endocrinology and Genetics, Boston Children's Hospital, Boston, Massachusetts, United States of America; Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
[20]
Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
[21]
Genomic Variation in Human Populations and Complex Diseases Unit, Human Genetics Foundation and Dept. of Medical Sciences, University of Turin, Turin, Italy.
[22]
Center for Basic and Translational Obesity Research and Divisions of Endocrinology and Genetics, Boston Children's Hospital, Boston, Massachusetts, United States of America; Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.
[23]
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Center for Complex Disease Genomics, Baltimore, Maryland, United States of America.
[24]
Human Genetics Center, Houston, Texas, United States of America.
[25]
Research Unit Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany.
[26]
Genomic Variation in Human Populations and Complex Diseases Unit, Human Genetics Foundation, Turin, Italy.
[27]
Centre for Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
[28]
Department of Medicine, Service of Gastroenterology and Hepatology, Lausanne, Switzerland.
[29]
Neurology Service, Hospital Clinic, Barcelona, Spain.
[30]
Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany.
[31]
MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
[32]
Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands; Sleep Wake Center SEIN, Heemstede, The Netherlands.
[33]
Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[34]
Department of Gastroenterology, University Hospital Basel, Basel, Switzerland.
[35]
Genetic Epidemiology, QIMR Berghofer Institute of Medical Research, Brisbane, Australia.
[36]
Molecular Epidemiology, QIMR Berghofer Institute of Medical Research, Brisbane, Australia.
[37]
Sleep and Epilepsy Unit - Clinical Neurophysiology Department, Gregorio Marañón University Hospital, Madrid, Spain.
[38]
Service of Gastroenterology and Hepatology, Service of Clinical Pathology, Geneva, Switzerland.
[39]
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
[40]
Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
[41]
Cardiovascular Science, National Heart & Lung Institute, Imperial College London, London, United Kingdom.
[42]
Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg, Germany; Deutsches Zentrum für Diabetes, Neuherberg, Germany.
[43]
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
[44]
Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[45]
Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[46]
Swiss Institute of Bioinformatics, Lausanne, Switzerland.
[47]
Center for Integrative Genomics (CIG), University of Lausanne, Lausanne, Switzerland; Center for Investigation and Research in Sleep (CIRS), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[48]
University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.
[49]
Estonian Genome Center, University of Tartu, Tartu, Estonia; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia; Estonian Biocentre, Tartu, Estonia.
[50]
Institute of Health Sciences, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Oulu, Finland; Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland; Department of Epidemiology and Biostatistics, School of Public Health, MRC-HPA Centre for Environment and Health, Faculty of Medicine, Imperial College London, London, United Kingdom; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.
[51]
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany; Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany.
[52]
MRC-Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom; The Charles Bronfman Institute of Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
[53]
Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
[54]
主题词
成年人(Adult);人体质量指数(Body Mass Index);女(雌)性(Female);基因表达调控(Gene Expression Regulation);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);基因组印迹(Genomic Imprinting);基因型(Genotype);葡萄糖转运蛋白质类, 易化性(Glucose Transport Proteins, Facilitative);人类(Humans);男(雄)性(Male);肥胖症(Obesity);多态性, 单核苷酸(Polymorphism, Single Nucleotide);钾通道, 双孔(Potassium Channels, Tandem Pore Domain)
DOI
10.1371/journal.pgen.1004508
PMID
25078964
发布时间
2022-12-07
- 浏览27
PLoS genetics
PLoS genetics
e1004508页
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