首页> Cancer discovery> Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.

Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma.

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第一作者： David,Chiron

第一单位： Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York.

作者： David,Chiron ^[1] ; Maurizio,Di Liberto ^[1] ; Peter,Martin ^[2] ; Xiangao,Huang ^[1] ; Jeff,Sharman ^[3] ; Pedro,Blecua ^[4] ; Susan,Mathew ^[1] ; Priyanka,Vijay ^[5] ; Ken,Eng ^[5] ; Siraj,Ali ^[6] ; Amy,Johnson ^[7] ; Betty,Chang ^[8] ; Scott,Ely ^[1] ; Olivier,Elemento ^[4] ; Christopher E,Mason ^[4] ; John P,Leonard ^[2] ; Selina,Chen-Kiang ^[9]

作者单位： Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York. ^[1] Department of Medicine, Weill Cornell Medical College, New York, New York. ^[2] Willamette Valley Cancer Institute and Research Center/US Oncology Research, Springfield, Oregon. ^[3] Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York. Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York. ^[4] Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York. Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medical College, New York, New York. ^[5] Foundation Medicine, Inc., Cambridge, Massachusetts. ^[6] Ohio State University, Columbus, Ohio. ^[7] Pharmacyclics, Sunnyvale, California. ^[8] Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York. Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Medical College, New York, New York. sckiang@med.cornell.edu. ^[9]