Polymorphisms in genes involved in the mechanism of action of methotrexate: are they associated with outcome in rheumatoid arthritis patients?
作者:
主题词
成年人(Adult);关节炎, 类风湿(Arthritis, Rheumatoid);生物学标记, 药理学(Biomarkers, Pharmacological);细胞周期蛋白D1(Cyclin D1);遗传关联研究(Genetic Association Studies);人类(Humans);羟甲基和甲酰转移酶类(Hydroxymethyl and Formyl Transferases);男(雄)性(Male);甲氨蝶呤(Methotrexate);亚甲基四氢叶酸还原酶(NADPH)(Methylenetetrahydrofolate Reductase (NADPH2));中年人(Middle Aged);多酶复合物(Multienzyme Complexes);核苷酸脱氨酶类(Nucleotide Deaminases);多态性, 单核苷酸(Polymorphism, Single Nucleotide);四氢叶酸脱氢酶(Tetrahydrofolate Dehydrogenase);治疗结果(Treatment Outcome)
DOI
10.2217/pgs.14.67
PMID
25084201
发布时间
2014-08-02
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Pharmacogenomics
1079-90页
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