Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.
第一作者:
Henna,Martiskainen
第一单位:
Institute of Clinical Medicine - Neurology, University of Eastern Finland, and Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
作者:
主题词
阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);载脂蛋白E类(Apolipoproteins E);脑(Brain);队列研究(Cohort Studies);疾病恶化(Disease Progression);女(雌)性(Female);基因检测(Genetic Testing);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);人类(Humans);男(雄)性(Male);神经心理学测验(Neuropsychological Tests);肽碎片(Peptide Fragments);多态性, 单核苷酸(Polymorphism, Single Nucleotide)
DOI
10.3233/JAD-140777
PMID
25096612
发布时间
2015-11-19
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