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首页> The EMBO journal> DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.

DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA.

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作者： Sihyun,Sung ^[1] ; Fuyang,Li ^[2] ; Young Bong,Park ^[1] ; Jin Seok,Kim ^[1] ; Ae-Kyoung,Kim ^[3] ; Ok-Kyu,Song ^[3] ; Jiae,Kim ^[1] ; Jun,Che ^[2] ; Sang Eun,Lee ^[4] ; Yunje,Cho ^[5]

作者单位： Department of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea. ^[1] Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. ^[2] Panbionet Corporation, Pohang, South Korea. ^[3] Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA Department of Radiation Oncology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA lees4@uthscsa.edu yunje@postech.ac.kr. ^[4] Department of Life Sciences, Pohang University of Science and Technology, Pohang, South Korea lees4@uthscsa.edu yunje@postech.ac.kr. ^[5]

关键词 DNA end recognition DSB repair Mre11‐DNA conserved basic region crystal structure

主题词氨基酸序列(Amino Acid Sequence);古细菌蛋白质类(Archaeal Proteins);结晶学, X线(Crystallography, X-Ray);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA突变分析(DNA Mutational Analysis);DNA, 古细菌(DNA, Archaeal);二聚作用(Dimerization);内切脱氧核糖核酸酶类(Endodeoxyribonucleases);脱氧核糖核酸外切酶类(Exodeoxyribonucleases);模型, 分子(Models, Molecular);模型, 结构(Models, Structural);分子序列数据(Molecular Sequence Data);蛋白质结合(Protein Binding);序列比对(Sequence Alignment)

DOI 10.15252/embj.201488299

PMID 25107472

发布时间 2021-10-21

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The EMBO journal

The EMBO journal

2014年33卷20期

2422-35页

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