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首页> PloS one> Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes.

Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes.

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作者： Synnøve,Magnussen ^[1] ; Elin,Hadler-Olsen ^[1] ; Nadezhda,Latysheva ^[1] ; Emma,Pirila ^[2] ; Sonja E,Steigen ^[3] ; Robert,Hanes ^[1] ; Tuula,Salo ^[4] ; Jan-Olof,Winberg ^[1] ; Lars,Uhlin-Hansen ^[3] ; Gunbjørg,Svineng ^[1]

作者单位： Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway. ^[1] Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland. ^[2] Department of Medical Biology, Faculty of Health Sciences, UiT - The Arctic University of Norway, Tromsø, Norway; Diagnostic Clinic - Department of Clinical Pathology, University Hospital of North Norway, Tromsø, Norway. ^[3] Department of Diagnostics and Oral Medicine, Institute of Dentistry, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland; Institute of Dentistry, University of Helsinki, Helsinki, Finland. ^[4]

主题词动物(Animals);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞系, 肿瘤(Cell Line, Tumor);培养基, 条件性(Culture Media, Conditioned);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);平滑肌瘤(Leiomyoma);基质金属蛋白酶2(Matrix Metalloproteinase 2);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠(Mice);肿瘤移植(Neoplasm Transplantation);受体, 尿激酶型纤溶酶原激活物(Receptors, Urokinase Plasminogen Activator);舌肿瘤(Tongue Neoplasms);转录激活(Transcriptional Activation);肿瘤微环境(Tumor Microenvironment)

DOI 10.1371/journal.pone.0105929

PMID 25157856

发布时间 2021-10-21

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PloS one

PloS one

2014年9卷8期

e105929页

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