HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization.

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作者： Marjon,Navis ^[1] ; Karen,Tran ^[2] ; Shridhar,Bale ^[3] ; Ganesh E,Phad ^[1] ; Javier,Guenaga ^[2] ; Richard,Wilson ^[2] ; Martina,Soldemo ^[1] ; Krisha,McKee ^[4] ; Christopher,Sundling ^[1] ; John,Mascola ^[4] ; Yuxing,Li ^[2] ; Richard T,Wyatt ^[5] ; Gunilla B,Karlsson Hedestam ^[1]

作者单位： Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. ^[1] IAVI Neutralizing Antibody Center at The Scripps Research Institute, La Jolla, California, United States of America. ^[2] Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America. ^[3] Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America. ^[4] IAVI Neutralizing Antibody Center at The Scripps Research Institute, La Jolla, California, United States of America; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America. ^[5]