换一批Enhanced mucosal immune responses against tetanus toxoid using novel delivery system comprised of chitosan-functionalized gold nanoparticles and botanical adjuvant: characterization, immunogenicity, and stability assessment.
第一作者：
Ganesh,Barhate
第一单位：
Department of Pharmaceutics, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune 411038, India; Serum Institute of India Ltd., 212/2, Hadapsar, Pune 411028, India.
作者：
医学主题词
佐剂, 免疫(Adjuvants, Immunologic);投药, 口服(Administration, Oral);动物(Animals);抗体, 细菌(Antibodies, Bacterial);芦笋植物(Asparagus Plant);化学, 药物(Chemistry, Pharmaceutical);壳聚糖(Chitosan);圆二色性(Circular Dichroism);药物载体(Drug Carriers);药物稳定性(Drug Stability);药物贮藏(Drug Storage);金(Gold);免疫, 黏膜(Immunity, Mucosal);免疫球蛋白A(Immunoglobulin A);免疫球蛋白G(Immunoglobulin G);金属纳米粒子(Metal Nanoparticles);小鼠(Mice);口腔黏膜(Mouth Mucosa);植物提取物(Plant Extracts);皂苷类(Saponins);光谱法, 荧光(Spectrometry, Fluorescence);谱学, 傅里叶变换红外(Spectroscopy, Fourier Transform Infrared);工艺学, 制药(Technology, Pharmaceutical);破伤风类毒素(Tetanus Toxoid);时间因素(Time Factors)
DOI
10.1002/jps.24161
PMID
25219511
发布时间
2017-09-17
- 浏览97
Journal of pharmaceutical sciences
3448-3456页
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