Reduced plasma angiotensin II levels are reversed by hydroxyurea treatment in mice with sickle cell disease.
作者:
主题词
贫血, 镰状细胞性(Anemia, Sickle Cell);血管紧张素Ⅱ(Angiotensin II);动物(Animals);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay);基因表达调控(Gene Expression Regulation);羟基脲(Hydroxyurea);肾(Kidney);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);肽基二肽酶A(Peptidyl-Dipeptidase A);受体, 血管紧张素, 1型(Receptor, Angiotensin, Type 1);受体, 血管紧张素, 2型(Receptor, Angiotensin, Type 2);肾素-血管紧张素系统(Renin-Angiotensin System)
DOI
10.1016/j.lfs.2014.08.021
PMID
25219880
发布时间
2020-12-09
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Life sciences
7-12页
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