A mitochondrial ATP synthase subunit interacts with TOR signaling to modulate protein homeostasis and lifespan in Drosophila.
第一作者:
Xiaoping,Sun
第一单位:
Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA.
作者:
医学主题词
动物(Animals);细胞周期蛋白质类(Cell Cycle Proteins);膳食, 低碳水化合物(Diet, Carbohydrate-Restricted);果蝇属(Drosophila);果蝇蛋白质类(Drosophila Proteins);女(雌)性(Female);基因表达调控(Gene Expression Regulation);激素拮抗药(Hormone Antagonists);长寿(Longevity);代谢网络和途径(Metabolic Networks and Pathways);米非司酮(Mifepristone);线粒体(Mitochondria);线粒体质子转运ATP酶(Mitochondrial Proton-Translocating ATPases);氧化性应激(Oxidative Stress);磷酰化(Phosphorylation);RNA干扰(RNA Interference);信号传导(Signal Transduction);西罗莫司(Sirolimus);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases)
DOI
10.1016/j.celrep.2014.08.022
PMID
25220459
发布时间
2025-05-29
- 浏览17
Cell reports
1781-1792页
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