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Studies on the anticonvulsant activity of 4-alkyl-1,2,4-triazole-3-thiones and their effect on GABAergic system.

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第一作者： Tomasz,Plech

第一单位： Department of Organic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: tomasz.plech@umlub.pl.

作者： Tomasz,Plech ^[1] ; Barbara,Kaproń ^[2] ; Jarogniew J,Luszczki ^[3] ; Agata,Paneth ^[2] ; Agata,Siwek ^[4] ; Marcin,Kołaczkowski ^[5] ; Maria,Żołnierek ^[4] ; Gabriel,Nowak ^[4]

作者单位： Department of Organic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: tomasz.plech@umlub.pl. ^[1] Department of Organic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. ^[2] Department of Pathophysiology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland; Isobolographic Analysis Laboratory, Institute of Rural Health, Jaczewskiego 2, 20-950 Lublin, Poland. ^[3] Department of Pharmacobiology, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland. ^[4] Department of Pharmaceutical Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland. ^[5]

关键词 1,2,4-Triazole-3-thiones Chimney test GABAergic system Maximal electroshock-induced seizure (MES) test Radioligand binding assay