换一批Synthesis and biological evaluation of benzothiazole derivatives bearing the ortho-hydroxy-N-acylhydrazone moiety as potent antitumor agents.
第一作者：
Junjie,Ma
第一单位：
Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenhe District, Shenyang, P. R. China.
作者：
医学主题词
抗肿瘤药(Antineoplastic Agents);苯并噻唑类(Benzothiazoles);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);药物设计(Drug Design);酶激活(Enzyme Activation);人类(Humans);腙类(Hydrazones);半数抑制浓度(Inhibitory Concentration 50);分子结构(Molecular Structure);肿瘤(Neoplasms);构效关系(Structure-Activity Relationship)
DOI
10.1002/ardp.201400230
PMID
25230149
发布时间
2014-12-02
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