Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.

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第一作者： Liang,Lu

第一单位： Departments of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294; Departments of Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294; Birmingham Veterans Affairs Medical Center, Birmingham, Alabama 35294, and. Electronic address: luliang@uab.edu.

作者： Liang,Lu ^[1] ; Lei,Zheng ^[2] ; Ying,Si ^[2] ; Wenyi,Luo ^[2] ; Gwendal,Dujardin ^[3] ; Thaddaeus,Kwan ^[2] ; Nicholas R,Potochick ^[4] ; Sunnie R,Thompson ^[4] ; David A,Schneider ^[5] ; Peter H,King ^[6]

作者单位： Departments of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294; Departments of Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294; Birmingham Veterans Affairs Medical Center, Birmingham, Alabama 35294, and. Electronic address: luliang@uab.edu. ^[1] Departments of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294. ^[2] Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires, Buenos Aires C1428EHA, Argentina. ^[3] Departments of Microbiology, and University of Alabama at Birmingham, Birmingham, Alabama 35294. ^[4] Departments of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294. ^[5] Departments of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294; Departments of Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294; Departments of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294; Birmingham Veterans Affairs Medical Center, Birmingham, Alabama 35294, and. ^[6]

关键词 3′ Untranslated Region Amyotrophic Lateral Sclerosis (ALS) (Lou Gehrig Disease)Astrocyte Neuron RNA Processing RNA Splicing