Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.-论文-万方医学网

作者： Altaf,Mohammed ^[1] ; Naveena B,Janakiram ^[2] ; Venkateshwar,Madka ^[2] ; Rebekah L,Ritchie ^[2] ; Misty,Brewer ^[2] ; Laura,Biddick ^[2] ; Jagan Mohan R,Patlolla ^[2] ; Michael,Sadeghi ^[2] ; Stan,Lightfoot ^[2] ; Vernon E,Steele ^[3] ; Chinthalapally V,Rao ^[1]

作者单位： Center for Cancer Prevention and Drug Development, Department of Medicine, Hem-Onc Section, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma. cv-rao@ouhsc.edu altaf-mohammed@ouhsc.edu. ^[1] Center for Cancer Prevention and Drug Development, Department of Medicine, Hem-Onc Section, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma. ^[2] Division of Cancer Prevention, Chemopreventive Agent Development Research Group, National Cancer Institute, Bethesda, Maryland. ^[3]

主题词动物(Animals);细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);癌, 胰腺管(Carcinoma, Pancreatic Ductal);细胞增殖(Cell Proliferation);疾病恶化(Disease Progression);依氟鸟氨酸(Eflornithine);女(雌)性(Female);人类(Humans);免疫酶技术(Immunoenzyme Techniques);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);突变(Mutation);鸟氨酸脱羧酶(Ornithine Decarboxylase);胰腺肿瘤(Pancreatic Neoplasms);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));RNA, 信使(RNA, Messenger);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1158/1940-6207.CAPR-14-0176

PMID 25248858

发布时间 2024-06-15

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Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.

Cancer prevention research (Philadelphia, Pa.)

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Cancer prevention research (Philadelphia, Pa.)

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Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.

Cancer prevention research (Philadelphia, Pa.)

相似文献

Cancer prevention research (Philadelphia, Pa.)

相关期刊

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