Vardenafil, a clinically available phosphodiesterase inhibitor, potentiates the killing effect of EGCG on CLL cells.
第一作者:
Motofumi,Kumazoe
第一单位:
Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
作者:
主题词
儿茶素(Catechin);细胞系, 肿瘤(Cell Line, Tumor);环核苷酸磷酸二酯酶类, 5型(Cyclic Nucleotide Phosphodiesterases, Type 5);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);药物协同作用(Drug Synergism);人类(Humans);咪唑类(Imidazoles);白血病, 淋巴细胞, 慢性, B细胞(Leukemia, Lymphocytic, Chronic, B-Cell);肿瘤蛋白质类(Neoplasm Proteins);磷酸二酯酶5抑制剂(Phosphodiesterase 5 Inhibitors);哌嗪类(Piperazines);受体, 层黏连蛋白(Receptors, Laminin);核糖体蛋白质类(Ribosomal Proteins);砜类(Sulfones);三嗪类(Triazines)
DOI
10.1111/bjh.13135
PMID
25250486
发布时间
2015-11-19
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