Protein corona change the drug release profile of nanocarriers: the "overlooked" factor at the nanobio interface.

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作者： Shahed,Behzadi ^[1] ; Vahid,Serpooshan ^[2] ; Ramin,Sakhtianchi ^[3] ; Beate,Müller ^[1] ; Katharina,Landfester ^[4] ; Daniel,Crespy ^[1] ; Morteza,Mahmoudi ^[5]

作者单位： Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. ^[1] Department of Pediatrics, Division of Cardiology, School of Medicine, Stanford University, Stanford, CA, United States. ^[2] Department of Nanotechnology and Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. ^[3] Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. Electronic address: landfester@mpip-mainz.mpg.de. ^[4] Department of Pediatrics, Division of Cardiology, School of Medicine, Stanford University, Stanford, CA, United States; Department of Nanotechnology and Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; Division of Cardiovascular Medicine, School of Medicine, Stanford University, Stanford, CA, United States. Electronic address: Mahmoudi@stanford.edu. ^[5]

关键词 Drug release profile Nanocarriers Polymeric shell Protein corona

主题词药物载体(Drug Carriers);纳米囊(Nanocapsules);纳米粒子(Nanoparticles);蛋白质类(Proteins)

DOI 10.1016/j.colsurfb.2014.09.009

PMID 25262409

发布时间 2014-12-08

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