The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.-论文-万方医学网

作者： Aura R,Garrison ^[1] ; Barbara G,Giomarelli ^[2] ; Calli M,Lear-Rooney ^[1] ; Carrie J,Saucedo ^[3] ; Srikanth,Yellayi ^[4] ; Lauren R H,Krumpe ^[3] ; Maura,Rose ^[2] ; Jason,Paragas ^[1] ; Mike,Bray ^[5] ; Gene G,Olinger ^[1] ; James B,McMahon ^[2] ; John,Huggins ^[1] ; Barry R,O'Keefe ^[6]

作者单位： Department of Viral Therapeutics, Virology Division, United States Army Medical Research Institute of Infectious Disease, Ft. Detrick, Frederick, MD 21702, United States. ^[1] Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States. ^[2] Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States; Basic Science Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States. ^[3] Office of the Chief Scientist, Integrated Research Facility, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, Frederick, MD 2170, United States. ^[4] Department of Viral Therapeutics, Virology Division, United States Army Medical Research Institute of Infectious Disease, Ft. Detrick, Frederick, MD 21702, United States; Division of Clinical Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892, United States. ^[5] Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States. Electronic address: okeefeba@mail.nih.gov. ^[6]

主题词动物(Animals);抗病毒药(Antiviral Agents);细菌蛋白质类(Bacterial Proteins);载体蛋白质类(Carrier Proteins);疾病模型, 动物(Disease Models, Animal);埃博拉病毒(Ebolavirus);糖蛋白类(Glycoproteins);出血热, 埃博拉(Hemorrhagic Fever, Ebola);半数抑制浓度(Inhibitory Concentration 50);注射, 皮下(Injections, Subcutaneous);外源凝集素类(Lectins);肝(Liver);马尔堡病毒属(Marburgvirus);膜蛋白质类(Membrane Proteins);小鼠, 近交BALB C(Mice, Inbred BALB C);微生物敏感性试验(Microbial Sensitivity Tests);血清(Serum);脾(Spleen);存活率分析(Survival Analysis);病毒包膜蛋白质类(Viral Envelope Proteins);病毒载量(Viral Load);病毒复制(Virus Replication)

DOI 10.1016/j.antiviral.2014.09.012

PMID 25265598

发布时间 2024-06-15

检索历史清除

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

Antiviral research

相似文献

Antiviral research

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

Antiviral research

相似文献

Antiviral research

相关期刊

检索历史清除