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首页> FASEB journal : official publication of the Federation of American Societies for Experimental Biology> Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis.

Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis.

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第一作者： Ivy A W,Ho

第一单位： Laboratory of Cancer Gene Therapy and.

作者： Ivy A W,Ho ^[1] ; Yulyana,Yulyana ^[1] ; Kian C,Sia ^[1] ; Jennifer P,Newman ^[1] ; Chang M,Guo ^[2] ; Kam M,Hui ^[3] ; Paula Y P,Lam ^[4]

作者单位： Laboratory of Cancer Gene Therapy and. ^[1] Department of Orthopedics, Singapore General Hospital, Singapore; ^[2] Bek Chai Heah Laboratory of Cancer Genomics, Cellular and Molecular Research Division, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore; Cancer and Stem Cells Biology Program, Duke-National University of Singapore Graduate Medical School, and Department of Biochemistry and Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), Singapore. ^[3] Laboratory of Cancer Gene Therapy and Cancer and Stem Cells Biology Program, Duke-National University of Singapore Graduate Medical School, and Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; and cmrlyp@nccs.com.sg. ^[4]

关键词 CXCR-4 MMP-1 MSCs SDF-1 migration

主题词细胞运动(Cell Movement);细胞, 培养的(Cells, Cultured);趋化因子CXCL12(Chemokine CXCL12);女(雌)性(Female);人类(Humans);男(雄)性(Male);基质金属蛋白酶1(Matrix Metalloproteinase 1);间质干细胞(Mesenchymal Stem Cells);中年人(Middle Aged);受体, PAR-1(Receptor, PAR-1);受体, CXCR4(Receptors, CXCR4);肿瘤微环境(Tumor Microenvironment)

DOI 10.1096/fj.14-252551

PMID 25271298

发布时间 2018-12-02

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FASEB journal

2014年28卷10期

4359-68页

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