Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.-论文-万方医学网

作者： Henna,Martiskainen ^[1] ; Jayashree,Viswanathan ^[2] ; Niko-Petteri,Nykänen ^[3] ; Mitja,Kurki ^[2] ; Seppo,Helisalmi ^[2] ; Teemu,Natunen ^[1] ; Timo,Sarajärvi ^[1] ; Kaisa M A,Kurkinen ^[1] ; Juha-Pekka,Pursiheimo ^[4] ; Tuomas,Rauramaa ^[5] ; Irina,Alafuzoff ^[6] ; Juha E,Jääskeläinen ^[7] ; Ville,Leinonen ^[7] ; Hilkka,Soininen ^[2] ; Annakaisa,Haapasalo ^[2] ; Henri J,Huttunen ^[3] ; Mikko,Hiltunen ^[8]

作者单位： Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. ^[1] Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland. ^[2] Neuroscience Center, University of Helsinki, Helsinki, Finland. ^[3] Turku Centre for Biotechnology, University of Turku, Turku, Finland. ^[4] Department of Pathology, Kuopio University Hospital, Kuopio, Finland; Institute of Clinical Medicine-Pathology, University of Eastern Finland, Kuopio, Finland. ^[5] Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. ^[6] Institute of Clinical Medicine-Neurosurgery, University of Eastern Finland, Kuopio, Finland; Neurosurgery of NeuroCenter, Kuopio University Hospital, Kuopio, Finland. ^[7] Institute of Clinical Medicine-Neurology, University of Eastern Finland, Kuopio, Finland; Department of Neurology, Kuopio University Hospital, Kuopio, Finland; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland. Electronic address: mikko.hiltunen@uef.fi. ^[8]

主题词衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);脑(Brain);女(雌)性(Female);基因表达(Gene Expression);基因表达谱(Gene Expression Profiling);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);男(雄)性(Male);膜糖蛋白类(Membrane Glycoproteins);膜蛋白质类(Membrane Proteins);神经原纤维(Neurofibrils);核蛋白质类(Nuclear Proteins);磷酰化(Phosphorylation);受体, 免疫(Receptors, Immunologic);危险(Risk);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);tau蛋白质类(tau Proteins)

DOI 10.1016/j.neurobiolaging.2014.09.003

PMID 25281018

发布时间 2022-03-21

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Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Neurobiology of aging

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Neurobiology of aging

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Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Neurobiology of aging

相似文献

Neurobiology of aging

相关期刊

检索历史清除