N-acetylgalactosaminide α2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathy.

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第一作者： Milada,Stuchlova Horynova

第一单位： Department of Immunology, Faculty of Medicine and Dentistry, Palacky University, Olomouc 77515, Czech Republic Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

作者： Milada,Stuchlova Horynova ^[1] ; Alena,Vrablikova ^[1] ; Tyler J,Stewart ^[2] ; Kazuo,Takahashi ^[3] ; Lydie,Czernekova ^[1] ; Koshi,Yamada ^[4] ; Hitoshi,Suzuki ^[4] ; Bruce A,Julian ^[5] ; Matthew B,Renfrow ^[6] ; Jan,Novak ^[2] ; Milan,Raska ^[1]

作者单位： Department of Immunology, Faculty of Medicine and Dentistry, Palacky University, Olomouc 77515, Czech Republic Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[1] Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[2] Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan. ^[3] Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan. ^[4] Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[5] Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ^[6]

关键词 IgA nephropathy aberrant O-glycosylation galactose-deficient IgA1 immunoglobulin A1 α2,6 sialyltransferase ST6GalNAc-II