Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
第一作者:
Tongmeng,Yan
第一单位:
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China, yantm1988@gmail.com.
作者:
主题词
成年人(Adult);老年人(Aged);癌, 肝细胞(Carcinoma, Hepatocellular);色谱法, 液相(Chromatography, Liquid);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);葡糖醛酸基转移酶(Glucuronosyltransferase);乙型肝炎(Hepatitis B);人类(Humans);同工酶类(Isoenzymes);肝肿瘤(Liver Neoplasms);男(雄)性(Male);质谱分析法(Mass Spectrometry);微粒体, 肝(Microsomes, Liver);中年人(Middle Aged);结果可重复性(Reproducibility of Results)
DOI
10.1007/s11095-014-1525-x
PMID
25288013
发布时间
2024-08-04
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Pharmaceutical research
1141-57页
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