Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.-论文-万方医学网

作者： Yuan,Lin ^[1] ; Haipeng,Zhang ^[1] ; Jiankai,Liang ^[1] ; Kai,Li ^[1] ; Wenbo,Zhu ^[1] ; Liwu,Fu ^[2] ; Fang,Wang ^[2] ; Xiaoke,Zheng ^[3] ; Huijuan,Shi ^[3] ; Sihan,Wu ^[1] ; Xiao,Xiao ^[1] ; Lijun,Chen ^[1] ; Lipeng,Tang ^[1] ; Min,Yan ^[1] ; Xiaoxiao,Yang ^[1] ; Yaqian,Tan ^[1] ; Pengxin,Qiu ^[1] ; Yijun,Huang ^[1] ; Wei,Yin ^[4] ; Xinwen,Su ^[1] ; Haiyan,Hu ^[5] ; Jun,Hu ^[6] ; Guangmei,Yan ^[7]

作者单位： Departments of Pharmacology. ^[1] State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510060, China; and. ^[2] Department of Pathology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. ^[3] Biochemistry, and. ^[4] School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510080, China; ^[5] Microbiology, Zhongshan School of Medicine and hujun@mail.sysu.edu.cn ygm@mail.sysu.edu.cn. ^[6] Departments of Pharmacology, hujun@mail.sysu.edu.cn ygm@mail.sysu.edu.cn. ^[7]

主题词甲病毒属(Alphavirus);动物(Animals);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);内质网(Endoplasmic Reticulum);女(雌)性(Female);基因表达谱(Gene Expression Profiling);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);显微镜检查, 电子, 透射(Microscopy, Electron, Transmission);肿瘤移植(Neoplasm Transplantation);肿瘤(Neoplasms);溶瘤病毒疗法(Oncolytic Virotherapy);溶瘤病毒(Oncolytic Viruses);RNA干扰(RNA Interference);组织阵列分析(Tissue Array Analysis);锌指(Zinc Fingers)

DOI 10.1073/pnas.1408759111

PMID 25288727

发布时间 2021-10-21

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Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.

Proceedings of the National Academy of Sciences of the United States of America

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Proceedings of the National Academy of Sciences of the United States of America

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Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers.

Proceedings of the National Academy of Sciences of the United States of America

相似文献

Proceedings of the National Academy of Sciences of the United States of America

相关期刊

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