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CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing.

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第一作者： Serena L,Chan

第一单位： Department of Microbiology and Molecular Genetics, School of Medicine, University of California at Irvine, Irvine, California 92697, USA;

作者： Serena L,Chan ^[1] ; Ina,Huppertz ^[2] ; Chengguo,Yao ^[1] ; Lingjie,Weng ^[3] ; James J,Moresco ^[4] ; John R,Yates ^[4] ; Jernej,Ule ^[2] ; James L,Manley ^[5] ; Yongsheng,Shi ^[1]

作者单位： Department of Microbiology and Molecular Genetics, School of Medicine, University of California at Irvine, Irvine, California 92697, USA; ^[1] Department of Molecular Neuroscience, University College London Institute of Neurology, London WC1N 3BG, United Kingdom; Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom; ^[2] Department of Microbiology and Molecular Genetics, School of Medicine, University of California at Irvine, Irvine, California 92697, USA; Institute for Genomics and Bioinformatics, Department of Computer Science, University of California at Irvine Irvine, California 92697, USA; ^[3] Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA; ^[4] Department of Biological Sciences, Columbia University, New York, New York 10027, USA. ^[5]

关键词 cleavage and polyadenylation mRNA 3′ processing polyadenylation signal