Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.

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作者： Koji,Yokoyama ^[1] ; Makoto,Ikeya ; Katsutsugu,Umeda ; Hirotsugu,Oda ; Seishiro,Nodomi ; Akira,Nasu ; Yoshihisa,Matsumoto ; Kazushi,Izawa ; Kazuhiko,Horigome ; Toshimasa,Kusaka ; Takayuki,Tanaka ; Megumu K,Saito ; Takahiro,Yasumi ; Ryuta,Nishikomori ; Osamu,Ohara ; Naoki,Nakayama ; Tatsutoshi,Nakahata ; Toshio,Heike ; Junya,Toguchida

作者单位： Kyoto University, Kyoto, Japan. ^[1]

主题词载体蛋白质类(Carrier Proteins);半胱氨酸天冬氨酸蛋白酶1(Caspase 1);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);软骨细胞(Chondrocytes);软骨发生(Chondrogenesis);冷吡啉相关周期性综合征(Cryopyrin-Associated Periodic Syndromes);环AMP(Cyclic AMP);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);环AMP依赖性蛋白激酶类(Cyclic AMP-Dependent Protein Kinases);葡糖氨基聚糖类(Glycosaminoglycans);人类(Humans);炎性体(Inflammasomes);突变(Mutation);表型(Phenotype);多潜能干细胞(Pluripotent Stem Cells);SOX9转录因子类(SOX9 Transcription Factor);信号传导(Signal Transduction)

DOI 10.1002/art.38912

PMID 25302486

发布时间 2016-11-25

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Arthritis & rheumatology (Hoboken, N.J.)

2015年67卷1期

302-14页

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Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

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Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

相关期刊

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