换一批
换一批FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
作者：
主题词
动物(Animals);细胞凋亡(Apoptosis);胆管肿瘤(Bile Duct Neoplasms);胆管, 肝内(Bile Ducts, Intrahepatic);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞周期(Cell Cycle);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);胆管上皮癌(Cholangiocarcinoma);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);上皮-间质转化(Epithelial-Mesenchymal Transition);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);肿瘤转移(Neoplasm Metastasis);磷酰化(Phosphorylation);丙二醇类(Propylene Glycols);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);鞘氨醇(Sphingosine);肿瘤负荷(Tumor Burden);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1186/1471-2407-14-783
PMID
25344679
发布时间
2024-05-09
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BMC cancer
783页
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