首页> Annals of oncology : official journal of the European Society for Medical Oncology> Translational studies within the TAMRAD randomized GINECO trial: evidence for mTORC1 activation marker as a predictive factor for everolimus efficacy in advanced breast cancer.

Translational studies within the TAMRAD randomized GINECO trial: evidence for mTORC1 activation marker as a predictive factor for everolimus efficacy in advanced breast cancer.

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第一作者： I,Treilleux

第一单位： Department of Anatomopathology, Centre Léon Bérard, Lyon.

作者： I,Treilleux ^[1] ; M,Arnedos ^[2] ; C,Cropet ^[3] ; Q,Wang ^[4] ; J-M,Ferrero ^[5] ; S,Abadie-Lacourtoisie ^[6] ; C,Levy ^[7] ; E,Legouffe ^[8] ; A,Lortholary ^[9] ; E,Pujade-Lauraine ^[10] ; A-V,Bourcier ^[11] ; J-C,Eymard ^[12] ; D,Spaeth ^[13] ; T,Bachelot ^[14]

作者单位： Department of Anatomopathology, Centre Léon Bérard, Lyon. ^[1] Oncology Department, Gustave Roussy, Villejuif. ^[2] Biostatistics and Therapeutic Evaluation Unit. ^[3] Genomic Platform-Translational Research Laboratory, Centre Léon Bérard, Lyon. ^[4] Medical Oncology Department, Centre Antoine Lacassagne, Nice. ^[5] Medical Oncology Department, Centre Paul Papin, Angers. ^[6] Oncology Department, Centre François Baclesse, Caen. ^[7] Hematology and Oncology Department, Clinique de Valdegour, Nimes. ^[8] Oncology Department, Centre Catherine de Sienne, Nantes. ^[9] Oncology Department, Université Paris Descartes, AP-HP, Hôpitaux Universitaires Paris Centre, Site Hôtel-Dieu, Paris. ^[10] Hematology and Oncology Department, Centre Hospitalier Départemental Les Oudairies, La Roche-Sur-Yon. ^[11] Department of Medicine, Institut Jean Godinot, Reims. ^[12] Oncology Department, Centre d'Oncologie de Gentilly, Nancy. ^[13] 2B North Department, Department of Medical Oncology and Cancer Research Center of Lyon, Centre Léon Bérard, Lyon, France. Electronic address: thomas.bachelot@lyon.unicancer.fr. ^[14]

关键词 biomarkers breast cancer everolimus mTORC1 tamoxifen