Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor.-论文-万方医学网

第一作者： Kurt,Schönfeld

第一单位： Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

作者： Kurt,Schönfeld ^[1] ; Christiane,Sahm ^[1] ; Congcong,Zhang ^[1] ; Sonja,Naundorf ^[2] ; Christian,Brendel ^[1] ; Marcus,Odendahl ^[3] ; Paulina,Nowakowska ^[4] ; Halvard,Bönig ^[4] ; Ulrike,Köhl ^[5] ; Stephan,Kloess ^[5] ; Sylvia,Köhler ^[1] ; Heidi,Holtgreve-Grez ^[6] ; Anna,Jauch ^[6] ; Manfred,Schmidt ^[7] ; Ralf,Schubert ^[8] ; Klaus,Kühlcke ^[2] ; Erhard,Seifried ^[4] ; Hans G,Klingemann ^[9] ; Michael A,Rieger ^[10] ; Torsten,Tonn ^[3] ; Manuel,Grez ^[1] ; Winfried S,Wels ^[11]

作者单位： Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany. ^[1] EUFETS GmbH, Idar-Oberstein, Germany. ^[2] Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East, Dresden and Transfusion Medicine, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany. ^[3] Institute for Transfusion Medicine and Immunohematology, Goethe University, and German Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt am Main, Germany. ^[4] Institute of Cellular Therapeutics, Hannover Medical School, Hannover, Germany. ^[5] Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany. ^[6] Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, Heidelberg, Germany. ^[7] Pediatric Pulmonology, Allergy and Cystic Fibrosis, University Hospital, Frankfurt am Main, Germany. ^[8] Conkwest Inc., Cardiff-by-the-Sea, California, USA. ^[9] 1] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany [2] Department of Hematology/Oncology, University Hospital, Frankfurt am Main, Germany [3] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[10] 1] Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany [2] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[11]

医学主题词动物(Animals);乳腺肿瘤(Breast Neoplasms);细胞系, 转化(Cell Line, Transformed);细胞系, 肿瘤(Cell Line, Tumor);细胞毒性, 免疫(Cytotoxicity, Immunologic);疾病模型, 动物(Disease Models, Animal);表位, T淋巴细胞(Epitopes, T-Lymphocyte);女(雌)性(Female);基因表达(Gene Expression);遗传载体(Genetic Vectors);人类(Humans);免疫表型分型(Immunophenotyping);免疫疗法(Immunotherapy);杀伤细胞, 天然(Killer Cells, Natural);慢病毒属(Lentivirus);淋巴细胞培养试验, 混合(Lymphocyte Culture Test, Mixed);肿瘤(Neoplasms);表型(Phenotype);受体, 免疫(Receptors, Immunologic);重组融合蛋白质类(Recombinant Fusion Proteins);转导, 遗传(Transduction, Genetic);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1038/mt.2014.219

PMID 25373520

发布时间 2021-10-21

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Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor.

Molecular therapy

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Molecular therapy

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Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor.

Molecular therapy

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同项目论文

Molecular therapy

相关期刊

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