Phosphorylation of the ribosomal protein S6, a marker of mTOR (mammalian target of rapamycin) pathway activation, is strongly increased in hypertrophic scars and keloids.
第一作者:
A,Andreoli
第一单位:
Swiss Tropical and Public Health Institute, Socinstr. 57, Basel, Switzerland.;University of Basel, Petersplatz 1, Basel, Switzerland.
作者:
医学主题词
肌动蛋白类(Actins);青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);瘢痕, 肥大性(Cicatrix, Hypertrophic);女(雌)性(Female);荧光抗体技术(Fluorescent Antibody Technique);人类(Humans);瘢痕疙瘩(Keloid);男(雄)性(Male);中年人(Middle Aged);肌, 平滑(Muscle, Smooth);磷酰化(Phosphorylation);核糖体蛋白质S6(Ribosomal Protein S6);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases)
DOI
10.1111/bjd.13523
PMID
25384444
发布时间
2021-12-03
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