换一批Targeting FoxM1 by thiostrepton inhibits growth and induces apoptosis of laryngeal squamous cell carcinoma.
第一作者：
Lizhu,Jiang
第一单位：
Department of Otolaryngology, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Rd, Chongqing, 400016, People's Republic of China.
作者：
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);癌, 鳞状细胞(Carcinoma, Squamous Cell);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);剂量效应关系, 药物(Dose-Response Relationship, Drug);减量调节(Down-Regulation);流式细胞术(Flow Cytometry);叉头转录因子类(Forkhead Transcription Factors);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);免疫组织化学(Immunohistochemistry);原位缺口末端标记(In Situ Nick-End Labeling);凋亡抑制蛋白质类(Inhibitor of Apoptosis Proteins);喉肿瘤(Laryngeal Neoplasms);小鼠(Mice);小鼠, 裸(Mice, Nude);分子靶向治疗(Molecular Targeted Therapy);随机分配(Random Allocation);信号传导(Signal Transduction);硫链丝菌肽(Thiostrepton);时间因素(Time Factors);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1007/s00432-014-1872-3
PMID
25391371
发布时间
2025-07-19
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