首页> Journal of immunology (Baltimore, Md. : 1950)> OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.

OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.

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第一作者： Sarah,Buchan

第一单位： Cancer Sciences Unit, Faculty of Medicine, University of Southampton.

作者： Sarah,Buchan ^[1] ; Teresa,Manzo ^[2] ; Barry,Flutter ^[2] ; Anne,Rogel ^[1] ; Noha,Edwards ^[2] ; Lei,Zhang ^[2] ; Shivajanani,Sivakumaran ^[2] ; Sara,Ghorashian ^[2] ; Ben,Carpenter ^[2] ; Clare,Bennett ^[2] ; Gordon J,Freeman ^[3] ; Megan,Sykes ^[4] ; Michael,Croft ^[5] ; Aymen,Al-Shamkhani ^[1] ; Ronjon,Chakraverty ^[2]

作者单位： Cancer Sciences Unit, Faculty of Medicine, University of Southampton. ^[1] Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London. ^[2] Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School. ^[3] Columbia Center for Translational Immunology, Columbia University Medical Center, New York. ^[4] Institute of Allergy and Immunology, La Jolla. ^[5]