Double negative (IgG+IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype.
第一作者:
Matteo,Bulati
第一单位:
Immunosenescence Unit, Department of Pathobiology and Medical and Forensic Biotechnologies (DIBIMEF), University of Palermo, Italy.
作者:
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);B淋巴细胞亚群(B-Lymphocyte Subsets);队列研究(Cohort Studies);女(雌)性(Female);流式细胞术(Flow Cytometry);人类(Humans);免疫球蛋白D(Immunoglobulin D);免疫球蛋白G(Immunoglobulin G);男(雄)性(Male);精神状态检查表(Mental Status Schedule);表型(Phenotype);受体, CCR6(Receptors, CCR6);受体, CCR7(Receptors, CCR7)
DOI
10.3233/JAD-142412
PMID
25408215
发布时间
2017-11-16
- 浏览15
Journal of Alzheimer's disease
1241-51页
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