HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer.

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作者： Hae Ryung,Chang ^[1] ; Seungyoon,Nam ^[1] ; Myeong-Cherl,Kook ^[2] ; Kyung-Tae,Kim ^[3] ; Xiuping,Liu ^[4] ; Hui,Yao ^[5] ; Hae Rim,Jung ^[1] ; Robert,Lemos ^[6] ; Hye Hyun,Seo ^[7] ; Hee Seo,Park ^[1] ; Youme,Gim ^[1] ; Dongwan,Hong ^[8] ; Iksoo,Huh ^[9] ; Young-Woo,Kim ^[10] ; Dongfeng,Tan ^[11] ; Chang-Gong,Liu ^[4] ; Garth,Powis ^[6] ; Taesung,Park ^[9] ; Han,Liang ^[5] ; Yon Hui,Kim ^[1]

作者单位： New Experimental Therapeutics Branch, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[1] Department of Pathology, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[2] Molecular Epidemiology Branch, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[3] Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[4] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[5] Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, California, USA. ^[6] Animal Sciences Branch, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[7] Cancer Genomics Branch, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[8] Department of Statistics, Seoul National University, Seoul, Republic of Korea. ^[9] Gastric Cancer Branch, National Cancer Center of Korea, Goyang-si, Kyeonggi-do, Republic of Korea. ^[10] Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. ^[11]

关键词 DRUG DEVELOPMENT GASTRIC CANCER GENE EXPRESSION MOLECULAR BIOLOGY ONCOGENES