Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance.
第一作者:
Yue,Yin
第一单位:
From the Institute of Human Virology and Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China and.
作者:
主题词
选择性剪接(Alternative Splicing);碱基序列(Base Sequence);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);基因表达调控(Gene Expression Regulation);HIV感染(HIV Infections);HIV-1(HIV-1);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);免疫记忆(Immunologic Memory);白细胞介素7(Interleukin-7);微RNAs(MicroRNAs);分子序列数据(Molecular Sequence Data);多聚嘧啶区结合蛋白质(Polypyrimidine Tract-Binding Protein);受体, 白细胞介素7(Receptors, Interleukin-7);信号传导(Signal Transduction);病毒载量(Viral Load);病毒复制(Virus Replication)
DOI
10.1074/jbc.M114.598631
PMID
25411246
发布时间
2021-02-05
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