换一批
换一批Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
第一作者：
Yu,Lan
第一单位：
Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology , Wuhan 430074, China.
作者：
主题词
动物(Animals);行为, 动物(Behavior, Animal);四氯化碳(Carbon Tetrachloride);快速延迟整流钾通道(Ether-A-Go-Go Potassium Channels);豚鼠(Guinea Pigs);小鼠(Mice);分子结构(Molecular Structure);运动活动(Motor Activity);神经痛(Neuralgia);神经保护药(Neuroprotective Agents);哌啶类(Piperidines);嘧啶类(Pyrimidines);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);受体, Σ(Receptors, sigma);构效关系(Structure-Activity Relationship)
DOI
10.1021/jm501207r
PMID
25420090
发布时间
2023-12-13
- 浏览22
Journal of medicinal chemistry
10404-23页
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