换一批
换一批IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis.
第一作者：
Ana I,Rovetta
第一单位：
a Departamento de Química Biológica; Facultad de Ciencias Exactas y Naturales; Universidad de Buenos Aires (UBA) ; Buenos Aires , Argentina.
作者：
关键词
AG, antigenATG, autophagy-relatedFBS, fetal bovine serumGAPDH, glyceraldehyde-3-phosphate dehydrogenaseGTP, guanosine triphosphateHD, healthy donorsHR TB, high-responder tuberculosis patientIFNGIFNG, interferon gammaIL, InterleukinLC3, microtubule-associated protein 1A/1B-light chain 3LR TB, low-responder tuberculosis patientsMtb-Ag, Mycobacterium tuberculosis antigenPBMC, peripheral blood mononuclear cellsPBS, phosphate-buffered salineSLAM, signaling lymphocytic activation moleculeTB, tuberculosisTh, T helperautophagycytokinesdefenseimmune responsemAb, monoclonal antibodypatientsrIFNG, recombinant IFNGtuberculosis
主题词
抗原, 细菌(Antigens, Bacterial);自噬(Autophagy);女(雌)性(Female);人类(Humans);干扰素γ(Interferon-gamma);巨噬细胞(Macrophages);男(雄)性(Male);结核分枝杆菌(Mycobacterium tuberculosis);Th1细胞(Th1 Cells);结核(Tuberculosis)
DOI
10.4161/15548627.2014.981791
PMID
25426782
发布时间
2018-11-13
- 浏览37
Autophagy
2109-21页
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