Identification, characterization, and structure analysis of the cyclic di-AMP-binding PII-like signal transduction protein DarA.

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作者： Jan,Gundlach ^[1] ; Achim,Dickmanns ^[2] ; Kathrin,Schröder-Tittmann ^[3] ; Piotr,Neumann ^[2] ; Jan,Kaesler ^[2] ; Jan,Kampf ^[1] ; Christina,Herzberg ^[1] ; Elke,Hammer ^[4] ; Frank,Schwede ^[5] ; Volkhard,Kaever ^[6] ; Kai,Tittmann ^[3] ; Jörg,Stülke ^[7] ; Ralf,Ficner ^[8]

作者单位： From the Departments of General Microbiology. ^[1] Molecular Structural Biology, and. ^[2] Molecular Enzymology, Georg August University Göttingen, 37077 Göttingen, Germany. ^[3] Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17487 Greifswald, Germany. ^[4] BIOLOG Life Science Institute, 28199 Bremen, Germany, and. ^[5] Research Core Unit Metabolomics, Hannover Medical School, 30625 Hannover, Germany. ^[6] From the Departments of General Microbiology, jstuelk@gwdg.de. ^[7] Molecular Structural Biology, and rficner@uni-goettingen.de. ^[8]

关键词 Bacterial Signal Transduction Crystal Structure Cyclic Di-GMP (c-di-GMP)Cyclic Diadenosine Monophosphate (c-di-AMP)Isothermal Titration Calorimetry (ITC)

主题词枯草芽孢杆菌(Bacillus subtilis);细菌蛋白质类(Bacterial Proteins);结晶学, X线(Crystallography, X-Ray);二核苷磷酸类(Dinucleoside Phosphates);蛋白质结构, 二级(Protein Structure, Secondary);蛋白质结构, 三级(Protein Structure, Tertiary);信号传导(Signal Transduction)

DOI 10.1074/jbc.M114.619619

PMID 25433025

发布时间 2021-02-05

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