Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue.
第一作者:
Lydia,Lynch
第一单位:
Department of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
作者:
主题词
脂肪组织(Adipose Tissue);动物(Animals);碱性亮氨酸拉链转录因子类(Basic-Leucine Zipper Transcription Factors);细胞生长过程(Cell Growth Processes);女(雌)性(Female);流式细胞术(Flow Cytometry);基因表达调控(Gene Expression Regulation);内环境稳定(Homeostasis);白细胞介素10(Interleukin-10);白细胞介素2(Interleukin-2);Kruppel样转录因子类(Kruppel-Like Transcription Factors);巨噬细胞(Macrophages);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);自然杀伤T细胞(Natural Killer T-Cells);无特异性病原体有机物(Specific Pathogen-Free Organisms);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory)
DOI
10.1038/ni.3047
PMID
25436972
发布时间
2024-06-10
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Nature immunology
85-95页
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