Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE.

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作者： Ellen T,McCarthy ^[1] ; Jianping,Zhou ^[2] ; Ryan,Eckert ^[2] ; David,Genochio ^[2] ; Rishi,Sharma ^[2] ; Olurinde,Oni ^[2] ; Alok,De ^[2] ; Tarak,Srivastava ^[3] ; Ram,Sharma ^[2] ; Virginia J,Savin ^[4] ; Mukut,Sharma ^[5]

作者单位： Kidney Institute, University of Kansas Medical Center, Kansas City, KS, United States. ^[1] Research Service, Kansas City VA Medical Center, Kansas City, MO, United States. ^[2] Research Service, Kansas City VA Medical Center, Kansas City, MO, United States; Section of Nephrology, Children's Mercy Hospital and University of Missouri at Kansas City, Kansas City, MO, United States. ^[3] Kidney Institute, University of Kansas Medical Center, Kansas City, KS, United States; Research Service, Kansas City VA Medical Center, Kansas City, MO, United States. ^[4] Kidney Institute, University of Kansas Medical Center, Kansas City, KS, United States; Research Service, Kansas City VA Medical Center, Kansas City, MO, United States. Electronic address: Mukut.sharma@va.gov. ^[5]

关键词 20-Carboxy-arachidonic acid 20-Hydroxyeicosatetraenoic Acid Alcohol dehydrogenase Chronic kidney disease Ethanol Glomerular filtration barrier Oxidative stress Podocytes Proteinuria

主题词醇脱氢酶(Alcohol Dehydrogenase);动物(Animals);细胞系, 转化(Cell Line, Transformed);细胞色素P450 CYP2E1(Cytochrome P-450 CYP2E1);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);乙醇(Ethanol);羟基花生四烯酸类(Hydroxyeicosatetraenoic Acids);肾疾病(Kidney Diseases);小鼠(Mice);足细胞(Podocytes);蛋白质合成抑制药(Protein Synthesis Inhibitors);嘌呤霉素(Puromycin)

DOI 10.1016/j.prostaglandins.2014.10.006

PMID 25447342

发布时间 2019-12-10

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Prostaglandins & other lipid mediators

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Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE.

Prostaglandins & other lipid mediators

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Prostaglandins & other lipid mediators

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Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE.

Prostaglandins & other lipid mediators

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Prostaglandins & other lipid mediators

相关期刊

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