换一批Dual targeting of the thioredoxin and glutathione antioxidant systems in malignant B cells: a novel synergistic therapeutic approach.
第一作者：
Michelle,Kiebala
第一单位：
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: michelle_kiebala@urmc.rochester.edu.
作者：
医学主题词
抗代谢药(Antimetabolites);抗肿瘤药(Antineoplastic Agents);金诺芬(Auranofin);B-淋巴细胞(B-Lymphocytes);丁硫氨酸硫酸亚胺(Buthionine Sulfoximine);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);药物协同作用(Drug Synergism);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);谷胱甘肽(Glutathione);人类(Humans);淋巴瘤, 膜细胞(Lymphoma, Mantle-Cell);分子靶向治疗(Molecular Targeted Therapy);NF-κB(NF-kappa B);氧化还原(Oxidation-Reduction);氧化性应激(Oxidative Stress);信号传导(Signal Transduction);硫氧还蛋白二硫化物还原酶(Thioredoxin-Disulfide Reductase);硫氧还蛋白质类(Thioredoxins)
DOI
10.1016/j.exphem.2014.10.004
PMID
25448488
发布时间
2018-11-13
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