Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.

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第一作者： Linda,Lee

第一单位： 1] Taub Institute and Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA [2] Department of Neurobiology and Behavior, Columbia University, New York, NY 10032, USA.

作者： Linda,Lee ^[1] ; Elena,Dale ^[2] ; Agnes,Staniszewski ^[2] ; Hong,Zhang ^[2] ; Faisal,Saeed ^[2] ; Mikako,Sakurai ^[2] ; Mauro,Fa' ^[2] ; Ian,Orozco ^[2] ; Francesco,Michelassi ^[2] ; Nsikan,Akpan ^[2] ; Helena,Lehrer ^[3] ; Ottavio,Arancio ^[2]

作者单位： 1] Taub Institute and Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA [2] Department of Neurobiology and Behavior, Columbia University, New York, NY 10032, USA. ^[1] Taub Institute and Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA. ^[2] Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. ^[3]

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);认知(Cognition);疾病模型, 动物(Disease Models, Animal);海马(Hippocampus);人类(Humans);长时程增强(Long-Term Potentiation);男(雄)性(Male);记忆(Memory);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);中年人(Middle Aged);神经元可塑性(Neuronal Plasticity);SUMO1蛋白(SUMO-1 Protein);SUMO化(Sumoylation)

DOI 10.1038/srep07190

PMID 25448527

发布时间 2018-11-13

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Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.

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Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease.

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