A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA.

导出 OA

翻译打印收藏纠错

作者： Michael R,White ^[1] ; Mohd M,Khan ^[1] ; Daniel,Deredge ^[2] ; Christina R,Ross ^[3] ; Royston,Quintyn ^[4] ; Beth E,Zucconi ^[3] ; Vicki H,Wysocki ^[4] ; Patrick L,Wintrode ^[2] ; Gerald M,Wilson ^[3] ; Elsa D,Garcin ^[5]

作者单位： From the Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, Maryland 21250. ^[1] Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, Maryland 21201. ^[2] Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland 21201, and. ^[3] Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210. ^[4] From the Department of Chemistry and Biochemistry, University of Maryland Baltimore County, Baltimore, Maryland 21250, egarcin@umbc.edu. ^[5]

关键词 AU-rich Elements Conformational Change Crystallography Fluorescence Anisotropy Fluorescence Resonance Energy Transfer (FRET)GAPDH Hydrogen Exchange Mass Spectrometry Oligomerization RNA Tumor Necrosis Factor (TNF)